Persistence of the bacterial pathogen Granulibacter bethesdensis in Chronic Granulomatous Disease monocytes and macrophages lacking a functional NADPH oxidase()

Granulibacter bethesdensis is a Gram-negative pathogen in patients with Chronic Granulomatous Disease (CGD), a deficiency in the phagocyte NADPH oxidase. Repeated isolation of genetically identical strains from the same patient over years, and prolonged waxing and waning seropositivity in some subje...

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Autors principals: Chu, Jessica, Song, Helen H., Zarember, Kol A., Mills, Teresa A., Gallin, John I.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769460/
https://ncbi.nlm.nih.gov/pubmed/23956436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300200
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