Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma

Angiosarcoma (AS) is a rare neoplasm of endothelial origin that has limited treatment options and poor five-year survival. As a model for human AS, we studied primary cells and tumorgrafts derived from canine hemangiosarcoma (HSA), which is also an endothelial malignancy with similar presentation an...

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Detalhes bibliográficos
Main Authors: Andersen, Nicholas J., Nickoloff, Brian J., Dykema, Karl J., Boguslawski, Elissa A., Krivochenitser, Roman I., Froman, Roe E., Dawes, Michelle J., Baker, Laurence H., Thomas, Dafydd G., Kamstock, Debra A., Kitchell, Barbara E., Furge, Kyle A., Duesbery, Nicholas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769440/
https://ncbi.nlm.nih.gov/pubmed/23804705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0893
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