The RRM1 domain of the poly(A)-binding protein from Saccharomyces cerevisiae is critical to control of mRNA deadenylation

The poly(A)-binding protein PAB1 from the yeast Saccharomyces cerevisiae plays an important role in controlling mRNA deadenylation rates. Deletion of either its RRM1 or proline-rich domain (P domain) severely restricts deadenylation and slows mRNA degradation. Because these large deletions could be...

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Autori principali: Zhang, Chongxu, Lee, Darren J., Chiang, Yueh-Chin, Richardson, Roy, Park, Shi Wha, Wang, Xin, Laue, Thomas. M., Denis, Clyde L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769428/
https://ncbi.nlm.nih.gov/pubmed/23793387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00438-013-0759-3
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