Analysis of Host Responses to Mycobacterium tuberculosis Antigens in a Multi-Site Study of Subjects with Different TB and HIV Infection States in Sub-Saharan Africa

BACKGROUND: Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are relevant to protective immunity in high-endemic are...

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Main Authors: Sutherland, Jayne S., Lalor, Maeve K., Black, Gillian F., Ambrose, Lyn R., Loxton, Andre G., Chegou, Novel N., Kassa, Desta, Mihret, Adane, Howe, Rawleigh, Mayanja-Kizza, Harriet, Gomez, Marie P., Donkor, Simon, Franken, Kees, Hanekom, Willem, Klein, Michel R., Parida, Shreemanta K., Boom, W. Henry, Thiel, Bonnie A., Crampin, Amelia C., Ota, Martin, Walzl, Gerhard, Ottenhoff, Tom H. M., Dockrell, Hazel M., Kaufmann, Stefan H. E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769366/
https://ncbi.nlm.nih.gov/pubmed/24040170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074080
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