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Fate of Pup inside the Mycobacterium Proteasome Studied by in-Cell NMR

The Mycobacterium tuberculosis proteasome is required for maximum virulence and to resist killing by the host immune system. The prokaryotic ubiquitin-like protein, Pup-GGE, targets proteins for proteasome-mediated degradation. We demonstrate that Pup-GGQ, a precursor of Pup-GGE, is not a substrate...

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Détails bibliographiques
Auteurs principaux: Maldonado, Andres Y., Burz, David S., Reverdatto, Sergey, Shekhtman, Alexander
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769308/
https://ncbi.nlm.nih.gov/pubmed/24040288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074576
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