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Fate of Pup inside the Mycobacterium Proteasome Studied by in-Cell NMR
The Mycobacterium tuberculosis proteasome is required for maximum virulence and to resist killing by the host immune system. The prokaryotic ubiquitin-like protein, Pup-GGE, targets proteins for proteasome-mediated degradation. We demonstrate that Pup-GGQ, a precursor of Pup-GGE, is not a substrate...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science
2013
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769308/ https://ncbi.nlm.nih.gov/pubmed/24040288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074576 |
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