Prion Protein Accumulation in Lipid Rafts of Mouse Aging Brain

The cellular form of the prion protein (PrP(C)) is a normal constituent of neuronal cell membranes. The protein misfolding causes rare neurodegenerative disorders known as transmissible spongiform encephalopathies or prion diseases. These maladies can be sporadic, genetic or infectious. Sporadic pri...

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Main Authors: Agostini, Federica, Dotti, Carlos G., Pérez-Cañamás, Azucena, Ledesma, Maria Dolores, Benetti, Federico, Legname, Giuseppe
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769255/
https://ncbi.nlm.nih.gov/pubmed/24040215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074244
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