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The Non-Structural NS1 Protein Unique to Respiratory Syncytial Virus: A Two-State Folding Monomer in Quasi-Equilibrium with a Stable Spherical Oligomer

Human respiratory syncytial virus (hRSV) is a major infectious agent that cause pediatric respiratory disease worldwide. Considered one of the main virulence factors of hRSV, NS1 is known to suppress type I interferon response and signaling, thus favoring immune evasion. This, together with the fact...

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Autori principali: Pretel, Esteban, Camporeale, Gabriela, de Prat-Gay, Gonzalo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769240/
https://ncbi.nlm.nih.gov/pubmed/24058549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074338
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