Unisexual and Heterosexual Meiotic Reproduction Generate Aneuploidy and Phenotypic Diversity De Novo in the Yeast Cryptococcus neoformans

Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer and genetic disorders such as trisomy 21 in Down's syndrome. In contrast, aneuploidy can also be advantageous and in fungi confers antifungal drug resistance and enables rapid adaptive evolution....

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Bibliografiske detaljer
Main Authors: Ni, Min, Feretzaki, Marianna, Li, Wenjun, Floyd-Averette, Anna, Mieczkowski, Piotr, Dietrich, Fred S., Heitman, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769227/
https://ncbi.nlm.nih.gov/pubmed/24058295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001653
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