Unisexual and Heterosexual Meiotic Reproduction Generate Aneuploidy and Phenotypic Diversity De Novo in the Yeast Cryptococcus neoformans

Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer and genetic disorders such as trisomy 21 in Down's syndrome. In contrast, aneuploidy can also be advantageous and in fungi confers antifungal drug resistance and enables rapid adaptive evolution....

Full description

Saved in:
Bibliographic Details
Main Authors: Ni, Min, Feretzaki, Marianna, Li, Wenjun, Floyd-Averette, Anna, Mieczkowski, Piotr, Dietrich, Fred S., Heitman, Joseph
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769227/
https://ncbi.nlm.nih.gov/pubmed/24058295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001653
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items