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Cheliensisin A Inhibits EGF-induced Cell Transformation with Stabilization of p53 Protein via a Hydrogen Peroxide/Chk1-dependent Axis
Cheliensisin A (Chel A), a novel styryl-lactone isolated from Goniothalamus cheliensis Hu, has been shown to induce of apoptosis in human promyelocytic leukemia HL-60 cells with Bcl-2 downregulation. Yet the potential chemopreventive effect of Chel A has not been explored. Here we demonstrated that...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769189/ https://ncbi.nlm.nih.gov/pubmed/23852422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0097 |
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