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Coupling fast water exchange to slow molecular tumbling in Gd(3+) chelates: why faster is not always better

The influence of dynamics on solution state structure is a widely overlooked consideration in chemistry. Variations in Gd(3+) chelate hydration with changing coordination geometry and dissociative water exchange kinetics substantially impact the effectiveness (or relaxivity) of mono-hydrated Gd(3+)...

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Autors principals: Avedano, Stefano, Botta, Mauro, Haigh, Julian S., Longo, Dario, Woods, Mark
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769110/
https://ncbi.nlm.nih.gov/pubmed/23841587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic400308a
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