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Peroxiredoxins as Molecular Triage Agents, Sacrificing Themselves to Enhance Cell Survival During a Peroxide Attack
In this issue of Molecular Cell, Day et al. (2012) reveal a surprising benefit of peroxiredoxin inactivation at high H(2)O(2), showing that in Schizosaccharomyces pombe turning off peroxide defenses preserves the pool of reduced thioredoxin for repairing proteins vital to survival.
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769099/ https://ncbi.nlm.nih.gov/pubmed/22325349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.012 |
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