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T Cell exhaustion in protozoan disease

Protozoan parasites cause severe morbidity and mortality in humans worldwide, especially in developing countries where access to chemotherapeutic agents is limited. Although parasites initially evoke a robust immune response, subsequent immunity fails to clear infection, ultimately leading to the ch...

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Bibliographic Details
Main Authors: Gigley, Jason P., Bhadra, Rajarshi, Moretto, Magali M., Khan, Imtiaz A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768288/
https://ncbi.nlm.nih.gov/pubmed/22832368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2012.07.001
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