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CTR1 Silencing Inhibits Angiogenesis by Limiting Copper Entry into Endothelial Cells
Increased levels of intracellular copper stimulate angiogenesis in human umbilical vein endothelial cells (HUVECs). Copper transporter 1 (CTR1) is a copper importer present in the cell membrane and plays a major role in copper transport. In this study, three siRNAs targeting CTR1 mRNA were designed...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767743/ https://ncbi.nlm.nih.gov/pubmed/24039729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071982 |
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