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An Improved Quantitative Approach for the Assessment of Mitochondrial Fragmentation in Chemoresistant Ovarian Cancer Cells

Mitochondrial fission is a process that involves cleavage of mitochondria into smaller fragments and is regulated by the GTPase Dynamin-related protein 1 (Drp1). Higher levels of mitochondrial fission are associated with the induction of apoptosis in cancer cells. However, current methods to accurat...

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Detalhes bibliográficos
Main Authors: Farrand, Lee, Kim, Ji Young, Im-Aram, Akechai, Suh, Jeong-Yong, Lee, Hyong Joo, Tsang, Benjamin K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767598/
https://ncbi.nlm.nih.gov/pubmed/24040144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074008
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