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Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog

Amino-terminal acetylation is a ubiquitous modification in eukaryotes that is involved in a growing number of biological processes. There are six known eukaryotic amino-terminal acetyltransferases (NATs), which are differentiated from one another on the basis of substrate specificity. To date, two e...

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Main Authors: Liszczak, Glen, Marmorstein, Ronen
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767502/
https://ncbi.nlm.nih.gov/pubmed/23959863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310365110
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