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Specificity and Versatility of Substrate Binding Sites in Four Catalytic Domains of Human N-Terminal Acetyltransferases

Nt-acetylation is among the most common protein modifications in eukaryotes. Although thought for a long time to protect proteins from degradation, the role of Nt-acetylation is still debated. It is catalyzed by enzymes called N-terminal acetyltransferases (NATs). In eukaryotes, several NATs, compos...

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Detalhes bibliográficos
Main Authors: Grauffel, Cédric, Abboud, Angèle, Liszczak, Glen, Marmorstein, Ronen, Arnesen, Thomas, Reuter, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532069/
https://ncbi.nlm.nih.gov/pubmed/23285125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052642
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