Comparison of anti-EGFR-Fab’ conjugated immunoliposomes modified with two different conjugation linkers for siRNa delivery in SMMC-7721 cells

BACKGROUND: Targeted liposome-polycation-DNA complex (LPD), mainly conjugated with antibodies using functionalized PEG derivatives, is an effective nanovector for systemic delivery of small interference RNA (siRNA). However, there are few studies reporting the effect of different conjugation linkers...

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Bibliografski detalji
Glavni autori: Deng, Li, Zhang, Yingying, Ma, Lulu, Jing, Xiaolong, Ke, Xingfa, Lian, Jianhao, Zhao, Qiang, Yan, Bo, Zhang, Jinfeng, Yao, Jianzhong, Chen, Jianming
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2013
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767494/
https://ncbi.nlm.nih.gov/pubmed/24023515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47597
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