Comparison of anti-EGFR-Fab’ conjugated immunoliposomes modified with two different conjugation linkers for siRNa delivery in SMMC-7721 cells

BACKGROUND: Targeted liposome-polycation-DNA complex (LPD), mainly conjugated with antibodies using functionalized PEG derivatives, is an effective nanovector for systemic delivery of small interference RNA (siRNA). However, there are few studies reporting the effect of different conjugation linkers...

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Bibliografiske detaljer
Main Authors: Deng, Li, Zhang, Yingying, Ma, Lulu, Jing, Xiaolong, Ke, Xingfa, Lian, Jianhao, Zhao, Qiang, Yan, Bo, Zhang, Jinfeng, Yao, Jianzhong, Chen, Jianming
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767494/
https://ncbi.nlm.nih.gov/pubmed/24023515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47597
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