Comparison of anti-EGFR-Fab’ conjugated immunoliposomes modified with two different conjugation linkers for siRNa delivery in SMMC-7721 cells

BACKGROUND: Targeted liposome-polycation-DNA complex (LPD), mainly conjugated with antibodies using functionalized PEG derivatives, is an effective nanovector for systemic delivery of small interference RNA (siRNA). However, there are few studies reporting the effect of different conjugation linkers...

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Detalhes bibliográficos
Main Authors: Deng, Li, Zhang, Yingying, Ma, Lulu, Jing, Xiaolong, Ke, Xingfa, Lian, Jianhao, Zhao, Qiang, Yan, Bo, Zhang, Jinfeng, Yao, Jianzhong, Chen, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767494/
https://ncbi.nlm.nih.gov/pubmed/24023515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47597
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