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Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia

Toll like receptors 7 (TLR7) and 9 (TLR9) are important mediators of innate immune responses. Both receptors are located in endosomal compartments, recognize nucleic acids and signal via Myeloid differentiation factor 88 (MyD88). In the current study, we analyzed TLR7 and TLR9 induced activation of...

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Autori principali: Butchi, Niranjan B., Du, Min, Peterson, Karin E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767435/
https://ncbi.nlm.nih.gov/pubmed/19998480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20952
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