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Synthesis of an Advanced Intermediate of the Jatrophane Diterpene Pl-4: A Dibromide Coupling Approach

[Image: see text] The preparation of an advanced intermediate toward the synthesis of the jatrophane diterpene Pl-4 is described. The key step is a regioselective chelation-controlled lithiation of the (Z)-configured bromide in the corresponding vinyl dibromide precursor. The method outlined within...

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Autori principali: Fürst, Rita, Rinner, Uwe
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2013
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767202/
https://ncbi.nlm.nih.gov/pubmed/23895274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo401480t
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