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Towards the Total Synthesis of Pl-3: Preparation of the Eastern Fragment through a Diastereoselective SmI(2)-Mediated Reformatsky Reaction
The jatrophane diterpene Pl-3, isolated in 2003 from Euphorbia platyphyllos, is a structurally complex natural product with highly promising biological properties that include pronounced antiproliferative activity and the inhibition of the efflux-pump activity of multidrug resistance p-glycoprotein....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654569/ https://ncbi.nlm.nih.gov/pubmed/23687456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201300148 |
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