Chitosan Enhances the Stability and Targeting of Immuno-Nanovehicles to Cerebro-vascular Deposits of Alzheimer’s Disease Amyloid Protein

Alzheimer's disease amyloid β (Aβ) proteins accumulate in the cerebral vasculature and cause cerebral amyloid angiopathy (CAA). The objective of this study is to resolve critical formulation issues in developing nanoparticles capable of permeating the blood brain barrier (BBB) and targeting cer...

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Hlavní autoři: Jaruszewski, Kristen M., Ramakrishnan, Subramanian, Poduslo, Joseph F., Kandimalla, Karunya K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767177/
https://ncbi.nlm.nih.gov/pubmed/21704598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2011.06.008
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