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Copy neutral loss of heterozygosity is more frequent in older ovarian cancer patients
Loss of heterozygosity (LOH) is a common type of genomic alterations in ovarian cancer. Analyzing 74,415 copy neutral LOH events in 513 serous ovarian adenocarcinomas samples from the Cancer Genome Atlas, we report that the frequency of LOH events increases with age. Similar trend is observed for ch...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767172/ https://ncbi.nlm.nih.gov/pubmed/23716468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22075 |
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