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Membrane curvature recognition by C-reactive protein using lipoprotein mimics

It has been reported that the oxidation of phosphatidylcholine (PC) is necessary for C-reactive protein (CRP) to bind to lipid membranes, but it remains elusive why CRP only binds oxidized membranes. Here we offer a new perspective on the role of membrane curvature and CRP binding using engineered l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Min S., Messersmith, Reid E., Reed, Scott M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767169/
https://ncbi.nlm.nih.gov/pubmed/24027600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SM25779C
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