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Development and characterization of NEX-Pten, a novel forebrain excitatory neuron-specific knockout mouse
The phosphatase and tensin homologue on chromosome 10 (PTEN) suppresses the activity of the phosphoinositide-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway, a signaling cascade critically involved in the regulation of cell proliferation and growth. Human patients carrying germline...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767032/ https://ncbi.nlm.nih.gov/pubmed/22572802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337229 |
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