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A gradient of Shh establishes mutually repressing somitic cell fates induced by Nkx3.2 and Pax3
Wnt and Sonic Hedgehog (Shh) signals are known to pattern the somite into dermomyotome, myotome and sclerotomal cell fates. By employing explants of presomitic mesoderm cultured with constant levels of Wnt3a conditioned medium and increasing levels of Shh, we found that differing levels of Shh signa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3766898/ https://ncbi.nlm.nih.gov/pubmed/18796301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.08.024 |
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