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BMP-mediated induction of GATA4/5/6 blocks somitic responsiveness to SHH
The relative timing of SHH and BMP signals controls whether presomitic mesoderm (PSM) cells will adopt either a chondrogenic or lateral plate mesoderm fate. Here we document that SHH-mediated induction of Nkx3.2 maintains the competence of somitic cells to initiate chondrogenesis in response to subs...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197703/ https://ncbi.nlm.nih.gov/pubmed/25294942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111906 |
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