The Use of Low Molecular Weight Protamine Chemical Chimera to Enhance Monomeric Insulin Intestinal Absorption

Although oral delivery of insulin offers a number of unmatched advantages, it nevertheless is beset by the poor permeability of insulin molecules through the epithelial cell membranes of the intestinal mucosal layer. We previously reported the development of low molecular weight protamine (LMWP) as...

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Hlavní autoři: He, Huining, Sheng, Jianyong, David, Allan E., Kwon, Young Min, Zhang, Jian, Huang, Yongzhuo, Wang, Jianxin, Yang, Victor C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766633/
https://ncbi.nlm.nih.gov/pubmed/23863452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.06.047
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