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Multiphasic DNA Adsorption to Silica Surfaces under Varying Buffer, pH, and Ionic Strength Conditions

Reversible interactions between DNA and silica are utilized in the solid phase extraction and purification of DNA from complex samples. Chaotropic salts commonly drive DNA binding to silica, but inhibit DNA polymerase amplification. We studied DNA adsorption to silica using conditions with or withou...

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Detalhes bibliográficos
Main Authors: Vandeventer, Peter E., Lin, Jessica S., Zwang, Theodore J., Nadim, Ali, Johal, Malkiat S., Niemz, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766398/
https://ncbi.nlm.nih.gov/pubmed/22537288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp3017776
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