Patient-derived tissue slice grafts accurately depict response of high-risk primary prostate cancer to androgen deprivation therapy

BACKGROUND: Effective eradication of high-risk primary prostate cancer (HRPCa) could significantly decrease mortality from prostate cancer. However, the discovery of curative therapies for HRPCa is hampered by the lack of authentic preclinical models. METHODS: We improved upon tumorgraft models that...

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Hauptverfasser: Zhao, Hongjuan, Thong, Alan, Nolley, Rosalie, Reese, Stephen W, Santos, Jennifer, Ingels, Alexandre, Peehl, Donna M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766103/
https://ncbi.nlm.nih.gov/pubmed/23985008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-199
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