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Tissue slice grafts of human renal cell carcinoma: An authentic preclinical model with high engraftment rate and metastatic potential

OBJECTIVE: Discovery of curative therapies for renal cell carcinoma (RCC) is hampered by lack of authentic preclinical models. Tumorgrafts, generated by direct implantation of patient-derived tissues into mice, have demonstrated superior ability to predict therapeutic response. We evaluated “tissue...

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Detalhes bibliográficos
Publicado no:Urol Oncol
Main Authors: Thong, Alan E., Zhao, Hongjuan, Ingels, Alexandre, Valta, Maija P., Nolley, Rosalie, Santos, Jennifer, Young, Sarah R., Peehl, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350678/
https://ncbi.nlm.nih.gov/pubmed/23911681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2013.05.008
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