Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities

BACKGROUND: The Y-box protein-1 (YB-1) fulfills pleiotropic functions relating to gene transcription, mRNA processing, and translation. It remains elusive how YB-1 shuttling into the nuclear and cytoplasmic compartments is regulated and whether limited proteolysis by the 20S proteasome releases frag...

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Hauptverfasser: van Roeyen, Claudia RC, Scurt, Florian G, Brandt, Sabine, Kuhl, Vanessa A, Martinkus, Sandra, Djudjaj, Sonja, Raffetseder, Ute, Royer, Hans-Dieter, Stefanidis, Ioannis, Dunn, Sandra E, Dooley, Steven, Weng, Honglei, Fischer, Thomas, Lindquist, Jonathan A, Mertens, Peter R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766096/
https://ncbi.nlm.nih.gov/pubmed/24103640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-63
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