Knockout of TLR4 and TLR2 impair the nerve regeneration by delayed demyelination but not remyelination

BACKGROUND: Knockout of either toll-like receptor 4 (TLR4) or 2 (TLR2) had been reported to delay the Wallerian degeneration after peripheral nerve injury by deterring the recruitment of the macrophages and clearance of myelin debris. However, the impact on the remyelination process is poorly unders...

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Библиографические подробности
Главные авторы: Wu, Shao-Chun, Rau, Cheng-Shyuan, Lu, Tsu-Hsiang, Wu, Chia-Jung, Wu, Yi-Chan, Tzeng, Siou-Ling, Chen, Yi-Chun, Hsieh, Ching-Hua
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765918/
https://ncbi.nlm.nih.gov/pubmed/23984978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-62
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