Knockout of TLR4 and TLR2 impair the nerve regeneration by delayed demyelination but not remyelination

BACKGROUND: Knockout of either toll-like receptor 4 (TLR4) or 2 (TLR2) had been reported to delay the Wallerian degeneration after peripheral nerve injury by deterring the recruitment of the macrophages and clearance of myelin debris. However, the impact on the remyelination process is poorly unders...

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Detalhes bibliográficos
Main Authors: Wu, Shao-Chun, Rau, Cheng-Shyuan, Lu, Tsu-Hsiang, Wu, Chia-Jung, Wu, Yi-Chan, Tzeng, Siou-Ling, Chen, Yi-Chun, Hsieh, Ching-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765918/
https://ncbi.nlm.nih.gov/pubmed/23984978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-62
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