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Vitamin B6 reduces hippocampal apoptosis in experimental pneumococcal meningitis

BACKGROUND: Bacterial meningitis caused by Streptococcus pneumoniae leads to death in up to 30% of patients and leaves up to half of the survivors with neurological sequelae. The inflammatory host reaction initiates the induction of the kynurenine pathway and contributes to hippocampal apoptosis, a...

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Autors principals: Zysset-Burri, Denise C, Bellac, Caroline L, Leib, Stephen L, Wittwer, Matthias
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765858/
https://ncbi.nlm.nih.gov/pubmed/23977941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-393
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