Doxycycline Reduces Mortality and Injury to the Brain and Cochlea in Experimental Pneumococcal Meningitis

Bacterial meningitis is characterized by an inflammatory reaction to the invading pathogens that can ultimately lead to sensorineural hearing loss, permanent brain injury, or death. The matrix metalloproteinases (MMPs) and tumor necrosis factor alpha-converting enzyme (TACE) are key mediators that p...

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Hlavní autoři: Meli, Damian N., Coimbra, Roney S., Erhart, Dominik G., Loquet, Gerard, Bellac, Caroline L., Täuber, Martin G., Neumann, Ulf, Leib, Stephen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489684/
https://ncbi.nlm.nih.gov/pubmed/16790761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01949-05
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