Disrupting the CXCL12/CXCR4 axis disturbs the characteristics of glioblastoma stem-like cells of rat RG2 glioblastoma

BACKGROUND: Glioblastoma stem-like cells (GSC) have been shown to promote tumor growth, tumor-associated neovascularization, therapeutic resistance, and metastasis. CXCR4 receptors have been found involved in the proliferation, metastasis, angiogenesis, and drug-resistant characteristics of glioblas...

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Detalhes bibliográficos
Main Authors: Lee, Chin-Cheng, Lai, Jin-Huei, Hueng, Dueng-Yang, Ma, Hsin-I, Chung, Yuan- Chiang, Sun, Ya-yun, Tsai, Yih-Ju, Wu, Wen-Ben, Chen, Chih-Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765790/
https://ncbi.nlm.nih.gov/pubmed/23961808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-85
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