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A new reporter mouse cytomegalovirus reveals maintained immediate-early gene expression but poor virus replication in cycling liver sinusoidal endothelial cells

BACKGROUND: The MCMV major immediate early promoter/enhancer (MIEP) is a bidirectional promoter that drives the expression of the three immediate early viral genes, namely ie1, ie2 and ie3. The regulation of their expression is intensively studied, but still incompletely understood. METHODS: We cons...

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Bibliographic Details
Main Authors: Dag, Franziska, Weingärtner, Adrien, Butueva, Milada, Conte, Ianina, Holzki, Julia, May, Tobias, Adler, Barbara, Wirth, Dagmar, Cicin-Sain, Luka
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765632/
https://ncbi.nlm.nih.gov/pubmed/23773211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-197
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