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Bioenergetic failure correlates with autophagy and apoptosis in rat liver following silver nanoparticle intraperitoneal administration

BACKGROUND: Deposition and accumulation of silver nanoparticles (Ag-nps) in the liver have been shown to induce hepatotoxicity in animal studies. The hepatotoxicity may include oxidative stress, abnormalities in energy metabolism, and cell death. Studies have indicated that autophagy is an intracell...

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Bibliografiske detaljer
Main Authors: Lee, Tzu-Ying, Liu, Maw-Shung, Huang, Li-Ju, Lue, Sheng-I, Lin, Lung-Chang, Kwan, Aij-Lie, Yang, Rei-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765627/
https://ncbi.nlm.nih.gov/pubmed/23958063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-10-40
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