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Bioenergetic failure correlates with autophagy and apoptosis in rat liver following silver nanoparticle intraperitoneal administration

BACKGROUND: Deposition and accumulation of silver nanoparticles (Ag-nps) in the liver have been shown to induce hepatotoxicity in animal studies. The hepatotoxicity may include oxidative stress, abnormalities in energy metabolism, and cell death. Studies have indicated that autophagy is an intracell...

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Detalhes bibliográficos
Main Authors: Lee, Tzu-Ying, Liu, Maw-Shung, Huang, Li-Ju, Lue, Sheng-I, Lin, Lung-Chang, Kwan, Aij-Lie, Yang, Rei-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765627/
https://ncbi.nlm.nih.gov/pubmed/23958063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-10-40
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