Trade-offs in quality of life and survival with chemotherapy for advanced breast cancer: mature results of a randomized trial comparing single-agent mitoxantrone with combination cyclophosphamide, methotrexate, 5-fluorouracil and prednisone

BACKGROUND: We evaluate trade-offs between quality of life (QoL) and survival improvement for two chemotherapy regimens in advanced breast cancer. We also report on the long-term survival of patients in the ANZ 8614 clinical trial. METHODS: A total of 391 patients were randomized to mitoxantrone (14...

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Detalhes bibliográficos
Main Authors: Lee, Chee Khoon, Gebski, Val J, Coates, Alan S, Veillard, Anne-Sophie, Harvey, Vernon, Tattersall, Martin HN, Byrne, Michael J, Brigham, Brian, Forbes, John, Simes, R John
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765591/
https://ncbi.nlm.nih.gov/pubmed/24024086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-391
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