Toll-like receptor 9 promoter polymorphism is associated with decreased risk of Alzheimer’s disease in Han Chinese

BACKGROUND: Toll-like receptors (TLRs), as major innate immune mediators, may be involved in clearance of cerebral amyloid-β (Aβ) deposits. Recently, a novel TLR9 signaling pathway has been uncovered, which is functionally associated with the immune inflammatory response and reducing Aβ burden in Al...

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Bibliographic Details
Main Authors: Wang, Ying-Li, Tan, Meng-Shan, Yu, Jin-Tai, Zhang, Wei, Hu, Nan, Wang, Hui-Fu, Jiang, Teng, Tan, Lan
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765501/
https://ncbi.nlm.nih.gov/pubmed/23957925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-101
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