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Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data

BACKGROUND: RTS,S is the most advanced candidate malaria vaccine but it is only partially protective and the causes of inter-individual variation in efficacy are poorly understood. Here, we investigated whether peripheral blood monocyte-to-lymphocyte ratios (ML ratio), previously shown to correlate...

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Detalhes bibliográficos
Main Authors: Warimwe, George M, Fletcher, Helen A, Olotu, Ally, Agnandji, Selidji T, Hill, Adrian VS, Marsh, Kevin, Bejon, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765422/
https://ncbi.nlm.nih.gov/pubmed/23962071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-11-184
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