Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes

The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We studied anti-mycobacterial function and the transcriptome of monocytes in relation to the ML ratio. Mycobacterial growth i...

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Publicado en:EBioMedicine
Main Authors: Naranbhai, Vivek, Fletcher, Helen A., Tanner, Rachel, O'Shea, Matthew K., McShane, Helen, Fairfax, Benjamin P., Knight, Julian C., Hill, Adrian V.S.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740301/
https://ncbi.nlm.nih.gov/pubmed/26870787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.09.027
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