TGFβ and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation

BACKGROUND: CCN2/CTGF is an established effector of TGFβ driven responses in diabetic nephropathy. We have identified an interaction between CCN2 and TGFβ leading to altered phenotypic differentiation and inhibited cellular migration. Here we determine the gene expression profile associated with thi...

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Detalhes bibliográficos
Main Authors: Faherty, Noel, O’Donovan, Helen, Kavanagh, David, Madden, Stephen, McKay, Gareth J, Maxwell, Alexander P, Martin, Finian, Godson, Catherine, Crean, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765338/
https://ncbi.nlm.nih.gov/pubmed/23902294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-525
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