CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte

In primary open-angle glaucoma (POAG), a neurodegenerative disease of the optic nerve (ON) and leading cause of blindness, the optic nerve head (ONH) undergoes marked structural extracellular matrix (ECM) changes, which contribute to its permanent deformation and to degeneration of ON axons. The rem...

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Detaylı Bibliyografya
Asıl Yazarlar: Andrea E. Dillinger, Gregor R. Weber, Matthias Mayer, Magdalena Schneider, Corinna Göppner, Andreas Ohlmann, Mikhail Shamonin, Gareth J. Monkman, Rudolf Fuchshofer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2022-04-01
Seri Bilgileri:Frontiers in Cell and Developmental Biology
Konular:
glaucoma
optic nerve
growth factors
astrocytes
stiffness
extracellar matrix
Online Erişim:https://www.frontiersin.org/articles/10.3389/fcell.2022.864433/full
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