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Haplotype phasing after joint estimation of recombination and linkage disequilibrium in breeding populations

A novel method for haplotype phasing in families after joint estimation of recombination fraction and linkage disequilibrium is developed. Results from Monte Carlo computer simulations show that the newly developed E.M. algorithm is accurate if true recombination fraction is 0 even for single famili...

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Main Authors: Gomez-Raya, Luis, Hulse, Amanda M, Thain, David, Rauw, Wendy M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765333/
https://ncbi.nlm.nih.gov/pubmed/23916349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-1891-4-30
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