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Maximum Likelihood Estimation of Linkage Disequilibrium in Half-Sib Families
Maximum likelihood methods for the estimation of linkage disequilibrium between biallelic DNA-markers in half-sib families (half-sib method) are developed for single and multifamily situations. Monte Carlo computer simulations were carried out for a variety of scenarios regarding sire genotypes, lin...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Genetics Society of America
2012
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338260/ https://ncbi.nlm.nih.gov/pubmed/22377635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.137521 |
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